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doi: 10.1016/j.arthro.2024.09.005

According to the Mounjaro Summary of Product Characteristics (SmPC), these two treatments do not have a known direct pharmacological interaction, as they work through entirely different mechanisms and are metabolised via separate pathways

Patients who had been enabled to self-treat over the pandemic embraced the change to their treatment and preferred this to standard treatment

Ideal candidates are research models with metabolic dysfunction characterized by both impaired insulin sensitivity and elevated adipose tissue NNMT expression common in diet-induced obesity, age-related metabolic decline, and type 2 diabetes models