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455 In addition, ferulic acid improves cognition dysfunction in copper-loaded Wilsons disease rats, suggesting that it reduces hippocampal neuron damage by activating SIRT1-mediated ferroptosis, providing a valuable drug candidate for the clinical treatment of cognitive impairment caused by Wilsons disease

Interestingly, the elevated blood homocysteine concentrations associated with riboflavin deficiency rapidly decline during alcohol withdrawal (30)

Overexpression of RNF146 inhibits OGD/R-induced increases in MDA and Fe 2+ , as well as the expression of ferroptosis related genes

9 3D BME-grown intestinal organoids maintain their transcriptional program with or without TS2/16