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It is also believed that the downstream products of these lipid peroxides, like malondialdehyde (MDA) and 4-hydroxy-nonenal (4-HNE), exert ferroptotic damage by degrading proteins or nucleic acids (Liu et al., 2020, 2021)

doi: 10.3389/fgene.2021.647246 129 KalinowskiALilientalJAnkerLALinkovskiOCulbertsonCHallJNet al

The extensive preclinical research foundation, favorable preclinical safety profile, and preliminary human experience suggest BPC-157 warrants continued investigation as a potential therapeutic agent for tissue repair and regeneration

[89] developed multifunctional neuron-targeted nanocomposites, IR780-Mn@TA-TPL NPs, for AD therapy (Fig