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Nat Rev Microbiol 2004

Higher level of oxidative damages to DNA in tumor cells with GSTP1 AA-genotype An enzyme-linked immunosorbent assay (ELISA) method was used to measure 8-OHdG, a marker of oxidative damage to DNA, in DNA extracted either from blood lymphocytes or tumor tissues of oral cancer patients who had the habit of RAN-chewing with and without tobacco (Fig