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Whether there are master regulatory genes impact many different types of NPs, or the reverse, if the NPs as LNC loaded with drugs based on proteins would affect target genes in a different manner between infected and normal cells, or an effect different from the free mRNA effect on this same gene, have yet to be discovered [140]

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Abrams RP, Carroll WL, Woerpel KA

Acetylation, methylation and phosphorylation are the best understood histone PTMs, but there are now at least 18 histone modifications known, and our knowledge of how they are involved in cellular function continues to expand