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These carriers can be engineered for surface modification with ligands targeting dopaminergic neurons or inflamed brain regions, enabling precision delivery and minimizing off-target toxicity (Naqvi et al., 2020

Zhang G, Zhong J, Lin L, Liu Z

This finding was supported by work in COS-7 cells demonstrating a 21-fold increased accumulation of DAG in cells transfected with desnutrin/ATGL compared with HSL, as well as a modest increase in MAG levels (144)

Non-invasive treatments like transcranial direct current stimulation (tDCS) and mindfulness-based interventions have shown potential for improving these outcomes, though their effects on stroke survivors remain unclear