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The top 20 transcription factors or chromatin regulators found in ChIP-seq experiments to bind to each gene was compiled, and the number of genes each factor bound to within the list of 61 was determined, with the top 9 regulators graphed, excluding the general factors EP300 and POL2RA

These results provide evidence that the reduction of peripheral GSH pools increases peripheral NGF circulation that orchestrates a neuroprotective response in the CNS, at least in the striatum, through the NGF/TrkA/Akt/Nrf2 pathway

During the degradation stage, the autophagosome fuses with a lysosome, and lysosomal hydrolases degrade its cargo

This in-turn compromised vitamin D regulatory genes