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Finally, there are two isoforms of SHMT in mammals, one cytoplasmic and the other mitochondrial 45,59,66 , and the same might be true for worms

Biochem Biophys Res Commun 438:721727 Li F, Rajendran P, Sethi G (2010) Thymoquinone inhibits proliferation, induces apoptosis and chemosensitizes human multiple myeloma cells through suppression of signal transducer and activator of transcription 3 activation pathway

Despite decades of research, no cure exists, and current treatments focus primarily on symptom management rather than altering the disease trajectory (Sun and Zhang, 2024)

Plantinga Y, Ghiadoni L, Magagna A, Giannarelli C, Franzoni F, Taddei S, Salvetti A