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To explain these experimental ndings, the corresponding potential energy surface of the S 1 state was constructed as a function of CoC and CoO bond distances, and the manifold of low-lying triplets was plotted as a function of CoC bond length

Destruction of the adrenal gland in primary AD creates a deficiency in all hormones it produces

*Correspondence: Gaobo Yu, [email protected] These authors have contributed equally to this work This article was submitted to Plant Metabolism and Chemodiversity, a section of the journal Frontiers in Plant Science Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Firstly, an increasing mRNA expression of various genes associated with an inhibitory effect on cell proliferation was observed, and secondly, a simultaneous increase was seen in the expression of HSD17B2 mRNA, responsible for the conversion of estradiol to its less biologically active formestrone [67,68]