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In addition, enhanced PTEN was also found to be involved in Kanglaite injection-induced apoptosis of human PCC cells [260]

Once in blood, while very low levels of TMP and thiamine circulate free in plasma or serum, more than 90% of the phosphorylated thiamine (in the form of TPP) is present in erythrocytes and leukocytes ( The cellular uptake of thiamine from the bloodstream can be mediated by any of the two high-affinity carriers: THTR1 [encoded by SLC19A2 ( SLC19A3 ( Figure 1B ]

10.1038/s41598-023-27575-7 50 HuangY.WangH.ChenZ.WangY.QinK.HuangY.et al (2019)

Abstract As an essential trace element, selenium (Se) plays a tremendous role in the functioning of the human organism being used for the biosynthesis of selenoproteins (proteins containing one or several selenocysteine residues)