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These investigations aim to optimize the safety and effectiveness of chemoradiotherapy regimens while simultaneously reducing the associated side effects [522].Additionally, in silico and in vitro studies have provided evidence that EGCG targets NF- B pathway, highlighting its potential as a therapeutic alternative for pancreatic cancer treatment by reducing cell growth, inducing apoptosis, and repressing NF- B target genes [523]

While it seems intuitive to massage the area, rubbing can increase bruising and irritation

The incidence of septic shock and severe sepsis in the USA is approximately 300/100,000 per year and cost more than $20 million in 2011 [4]

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