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10.1016/j.neuropharm.2021.108719 3 AshrafA.JeandriensJ.ParkesH

Ken Geraldi, Ms

Figure 1 2.1 Overproduction of ROS One hallmark feature of IBD is the overproduction of ROS, which causes dysregulation of signal transduction, an inflammatory response, and DNA damage, all of which contribute to the progression and deterioration of the disease (27)