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This idea is consistent with the current body of science, which indicates that genetics account for 20%25% of an individual's lifespan, while the remaining 75%80% is determined by various factors but principally lifestyle (5658)

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8, 9, 10 The perception that a breach in the mucosal barrier incites mucosal inflammation is supported by the physical location of the intestinal epithelium, interposed as it is between the luminal contents and the mucosal surface (Figure 1)