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When the microbiome is disrupted, Candida shifts into an invasive form that penetrates the gut lining, releases toxic metabolites, and triggers a cascade of symptoms that can span every system in the body: fatigue, brain fog, recurrent infections, skin problems, and mood instability

This has led to cases of compartment syndrome, a dangerous condition where pressure builds up within an enclosed muscle, restricting blood flow, and causing a limb-threatening emergency

In AD, DNA hypermethylation has been reported in the promoters of genes involved in synaptic plasticity, memory formation, and neuroinflammation, potentially contributing to the cognitive decline and neurodegeneration (156, 157)

Zheng J-L, Yuan S-S, Wu C-W et al (2017) Circadian time-dependent antioxidant and inflammatory responses to acute cadmium exposure in the brain of zebrafish