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Description

Absorption is extremely rapid owing to the lipophilic structure of heroin, even though its alkaline pK a (7.95) results in the predominance of the ionized form in the acidic alveolar subphase fluid (pH 6.9

Despite their diversity, all subunits of nAChRs possess a shared structural pattern

Capron et al ., Reference Capron, Beghin, Leclercq, Labreuche, Dendooven, Standaert, Delbeke, Porcherie, Nachury, Boruchowicz, Dupas, Fumery, Paupard, Catteau, Deplanque, Colombel and Desreumaux2019), two involved patients with UC (Summers et al ., Reference Summers, Elliott, Urban, Thompson and Weinstock2005 b