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The groups that genuinely warrant attention are people with severe malabsorption such as Crohn disease, those receiving long-term parenteral nutrition without added selenium, those on long-term hemodialysis, which removes selenium from the blood, people living with HIV, and people on very restricted diets, including medical diets such as those used in phenylketonuria

A swift increase in blood-brain barrier permeability within epileptogenic brain regions was also observed during magnetic resonance imaging in this particular animal model (169)

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