interaction of chloroacetamide electrophiles with cellular glutathion

interaction of chloroacetamide electrophiles with cellular glutathion Electrophilic compound screening identifies GPX4-dependent ferroptosis as a senescence vulnerability Expanding the Chemistry of Dihaloacetamides

Name: interaction of chloroacetamide electrophiles with cellular glutathion Electrophilic compound screening identifies GPX4-dependent ferroptosis as a senescence vulnerability Expanding the Chemistry of Dihaloacetamides
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Expanding the Chemistry of Dihaloacetamides as Tunable Electrophiles for Reversible Covalent Targeting of Cysteines Journal of Medicinal Chemistry The Selenoprotein Glutathione Peroxidase 4: From Molecular Mechanisms to Novel Therapeutic Opportunities Glutathione dynamics in subcellular compartments and implications for drug development ScienceDirect Glutathione Transferases: Potential Targets to Overcome Chemoresistance in Solid Tumors

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and inhibition of tumor stem cells

10.1016/j.psyneuen.2011.04.012 6 AsadiS.GholamiM

doi: 10.3389/fpls.2023.1119076 200 YangZ.ManJ.LiuH.WuD.GuQ.ZhangH.et al

Cancer Res 56:36783681 Gundimeda U, Schiffman JE, Chhabra D, Wong J, Wu A, Gopalakrishna R (2008) Locally generated methylseleninic acid induces specific inactivation of protein kinase C isoenzymes: relevance to selenium-induced apoptosis in prostate cancer cells