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The heart wall is made up of three layers: the myocardium (heart muscle tissue), the endocardium (which protects the valves and chambers), and the pericardium (a thin protective covering) [29]

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Furthermore, similar to bacteria (Prinz et al ., 1997), a quadruple trx1 trx2 grx1 grx2 yeast mutant is nonviable and a single functional disulphide reductase system is necessary for viability (Draculic et al ., 2000)