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This blockade prolongs the myocardial action potential, contributing to QT interval prolongation and increased vulnerability to malignant arrhythmias such as ventricular tachycardia and fibrillation

Applying techniques such as ChIP-chip, ChIP-Seq, ChIP-exo and CUT&RUN, and bioinformatics tools, the work of multiple groups has defined the genome-wide landscape of AR binding sites in CaP cell lines and tissues, which has allowed to more closely examine and characterize the corresponding DNA sequences [53]

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El ejercicio intenso conduce a niveles de acumulacin de amonaco en el tejido muscular que conduce a la fatiga