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In an experimental animal model of diabetes, high levels of nicotinamide are administered to protect -cells from damage caused by streptozotocin (69)

The problem is, few pediatricians get the word out and/or not many follow through with the advice

This is evidenced by the fact that we have now identified two different classes of drug, lobeline (monoamine metabolism) and raloxifene (SERM) that clearly function through different mechanisms yet yield the same result: delayed SG disassembly, prolonged ISR activation and increased GBM cell death

While oral Vitamin C saturates at serum levels of about 0.25 mM , IV Vitamin C can reach concentrations over 30 mM , more than 100 times higher (Levine 2011)