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Persistent cognitive impairment, hippocampal atrophy and EEG changes in sepsis survivors

It has been suggested that mast cells are the immune gate of the brain, and are likely associated with neuropathologic processes including MS (74)

SAM, as the key methyl donor for transmethylation reactions, its reduction directly weakens the efficiency of DNA and histone methylation modifications

such improvements may include, but are not limited to, autism severity, verbal communication, developmental status, and/or behaviour issues such as emotional reactions