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First in vivo demonstration that lentiviral-mediated somatic transduction of oncogenic MET in hepatocytes of adult mice leads to the development of hepatocellular carcinomas

Understanding whether these metabolic changes contribute to inflammation, synovial hypertrophy and cartilage damage will provide a novel insight of the progression and perpetuation of RA and will provide new therapeutic approaches for clinical use

Ipamorelin, a selective pentapeptide ghrelin mimetic, functions via the growth hormone secretagogue receptor (GHS-R1a) to stimulate acute GH exocytosis with high specificity and minimal impact on other pituitary axes in experimental assays