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Median CAGE-B score was 8 (IQR 6 -11), 20% was classified as low, 53% as intermediate and 27% as high risk

Strains : aox1 (red dashed line), aox1 , das1 : aox1::TDH3p , PGK1p and das1 (yellow line), aox1 , das1 , das2::TKL1p : aox1 :: TDH3p , PGK1p , das1 and das2 :: TKL1p (dark blue line), aox1 , das1 , das2 : aox1 :: TDH3p , PGK1p , das1 and das2 (blue line) and CBBRuBisCO : aox1 :: TDH3p , PRKp , PGK1p , das1 and das2 :: TPI1p , TKL1p , Each clone was cultivated in duplicates (error bars indicate s.e.m .) and the aox1 control was cultivated as triplicate (error bars show s.d

Antioxidants is very important for this phase, to neutralize toxic metabolites as chemicals are broken down