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Cancer cells can upregulate acetyl-CoA synthetase 2 (ACSS2) expression to generate acetyl-CoA from acetate [82] or upregulate ATP-citrate lyase (ACLY) expression to convert citrate to acetyl-CoA [83]

In each measurement, the samples and standards were assayed in three replicates each, and the average value was used to represent the test results

Many individuals remain undiagnosed unless identified through routine screening or family history evaluation

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