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Finkelstein JD

Other participants in the TCA cycle are also more active in KRAS-mutant tumors, particularly in pancreatic ductal adenocarcinoma (PDAC), where the increased expression of GOT1/2 supports glutamine metabolism while producing NADPH to maintain REDOX balance [50]

These mechanisms allow cells to increase their mutation rate and their ability to evolve preferentially when they are poorly adapted to their environment, that is, when stressed 15,180,181

Consultation with Healthcare Provider: Before starting treatment with Tationil, individuals should consult with a healthcare professional to evaluate their medical history and current health status