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In the early stages of AMD (i.e., dry AMD), drusen deposition, otherwise known as lipid depositions, is detected between the retinal pigment epithelium (RPE) and the Bruchs membrane [78] (Figure 5)

doi: 10.3389/FCELL.2022.943606 19

The difference is even more pronounced for PfGrx C32S/C88S

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