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This pairing is most useful when chronic inflammation is actively blocking repair conditions like IBD flares, post-surgical inflammation, or injuries where swelling persists beyond the normal acute window

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It was validated by immunohistochemistry in human samples, showing lower c-Jun-phosphorylation and down-regulation of pro-apoptotic genes in normal oral epithelial cells with the AA-genotype

A similar trend was observed with liver where GSH levels were significantly higher at 1% and 5% pesticide contamination (Table 2)