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McGarry JD, Brown NF (1997)

For instance, are you sleeping and eating enough

Targeting the ATF4-dependent autophagy pathway could offer a therapeutic approach for patients with Fms-like tyrosine kinase 3 (FLT3) mutations, as Fms-like tyrosine kinase 3 internal tandem duplication (FLT3-ITD) expression increases basal autophagy, which is essential for AML cell survival (40)