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doi: 10.1007/s00455-024-10756-5 41 PazdrowskiJGornowicz-PorowskaJKamierskaJKrajka-KuniakVPolanskaAMasternakMet al

Activated neutrophils drawn to the inflamed mucosa increase oxygen demands and promote regional hypoxia, with adenine and succinate liberated by cell necrosis and with HIF expressed by the intestinal epithelium

& Pascual, A

It is host to trillions of microorganisms - we're talking bacteria, fungi, viruses and even parasites (and yes, I know that last one doesn't sound so nice!)