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In males, we observed very similar results to those we found in females, with significant downregulation of p-S240/S244 S6 and T37/S46 4E-BP1 in the CR-fed group compared to the AL-fed group (Fig

In response to the generation of free oxygen radicals (ROS) by the male reproductive system cells, the hypothalamic-pituitary-adrenal axis is activated and cortisol is produced in response to stress