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If the abovementioned is occurring, it could mean that IGF-1 administration could also lower glucose levels by suppressing hepatic gluconeogenesis, as well as improving insulin signalling in this organ, leading to IGFBP-1 suppression and overall improvement of the IGF-1/GH/insulin axis

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However, its important to follow proper protocols and consult with healthcare professionals

However, many of Metformins potential longevity-related benefits, like cellular repair, improved metabolic markers, or disease prevention, happen silently and build over months or years