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Researchers looked at dietary histories of nearly 80,000 women in the Nurses' Health Study (NHS) and over 42,000 men in the Health Professionals Follow-up Study (HPFS) to determine whether repeated caffeine intake throughout the day would sustain IOP elevation and increase the risk of developing primary open angle glaucoma

A decrease in mitochondrial membrane potential may indicate apoptosis or other cellular damage processes [31]

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Due to oxidative stress caused by iron and ferroptosis caused by excitatory amino acid synergy, a large number of clinical trials on anti-amino acid toxicity and antioxidative stress treatment have been conducted