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doi:10.1183/09031936.04.00016804 6 Rushworth, G

And now it is generally believed that alcohol is harmful to the human gut, leading to a substantial number of IBD patients voluntarily refraining from alcohol consumption [274]

10.1016/J.CBPA.2017.02.006 Summary Keywords GAL4, cyclic peptide, combinatorial library, yeast two-hybrid, protein interference, galactose metabolism, drug discovery Citation Rosa S, Tagliani A, Bertaso C, Tadini L, Visentin C, Gourlay LJ, Pricl S, Feni L, Pellegrino S, Pesaresi P and Masiero S (2023) The cyclic peptide G4CP2 enables the modulation of galactose metabolism in yeast by interfering with GAL4 transcriptional activity

When the active substance circulates via the bloodstream, a fraction of the active substance will be metabolized or excreted, and consequently the concentration of the active substance in the body will decrease over time (see figure above)