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The AOD-9604 vs MOTS-c discussion in this context heavily favors MOTS-cs systemic benefits

The Master Switch: It rapidly activates a gene called Egr-1, which acts as a master controller to start building the proteins and vessels needed to close a wound

These findings highlight the potential therapeutic role of vitamin B12 as an epidrug in attenuating hyperinflammation, providing promising directions for further research in neuroinflammatory conditions associated with long COVID