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57 This study suggests the feasibility of targeting BCAAs metabolism in TME mesenchymal and cancer cells for PDAC therapy (Fig

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Resveratrol neuroprotection in stroke and traumatic CNS injury

Potent antioxidant function at the expense of central carbon metabolism The dependency of NRF2-addicted cancer cells on exogenous glutamine is attributable to the elevated consumption and excretion of glutamate as a result of two major transcriptional outputs of NRF2 (Fig