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The SCALE phase 3a trials discussed in this paper were designed prior to the recent regulatory requirements for intercurrent events and hence patients discontinuing randomized injections or violating the protocol were withdrawn from the trials and only invited in for a landmark visit to assess the body weight

Vitamin B12 shots are generally safe for most individuals, especially those with a B12 deficiency

Using a sterile syringe and needle, your provider will draw up the prescribed dose of vitamin B12 and inject it at a 90-degree angle into the muscle

Therefore, even if you have normal B12 levels, high homocysteine may expose a case of B12 deficiency