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Recently, the novel CI inhibitor IACS-010759 has demonstrated a promising inhibitory effect on cancer cells with high OXPHOS dependency, including PDAC [116]

To determine whether the failure of Ect2 to localize to cell borders under DP KD conditions was due to concurrent perturbations to AJs, we sought to assess the status of the cardiac AJ components, -catenin and N-cadherin, via immunofluorescence analysis in a DP-deficient background

A meta-analysis of published and unpublished data including patient data provided by the manufacturer examined 15 random controlled trials of 1046 patients who had taken erdosteine for at least 10 days

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