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These pathways offer valuable targets for developing new therapeutic approaches with reduced side effects and the potential for targeted elimination of pathological cells

The authors wish to thank Dr Patrick Fueger (Comprehensive Metabolic Phenotyping Core Facility) for assistance in the indirect calorimetry studies, Dr Lu Yang and Dr Xiwei Wu (Integrative Genomics and Bioinformatics Core) and Dr Yate-Ching Yuan (Division of Research Informatics) for the help in RNA sequencing data analyses and database submission, and Mrs

This, in turn, stimulates the lysosomal degradation of ferritin, resulting in increased intracellular iron ion concentration and the induction of ferroptosis

DO NOT reuse, as this can cause deterioration or separation of the rubber and pose a choking hazard