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Therefore, it is proposed that TRPC represent store-operated Ca 2+ entry channels (SOCE), as they play a key role in increasing cytoplasmic Ca 2+ (DeHaven et al., 2009

Typical Post-Injection Timeline First 24-48 hours: Mild to moderate pain at the injection site Localized warmth and redness Slight swelling around the knee Temporary stiffness or reduced range of motion Days 2-3: Gradual reduction in swelling Decreased pain and tenderness Return to normal mobility Possible spongy sensation when walking [4] The American Academy of Orthopaedic Surgeons notes that patients should avoid excessive activity, such as jogging or heavy lifting for the first 48 hours after injection [2]

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Additionally, professional athletes should verify anti-doping rules before considering use