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CBD acts as an agonist of the receptors/channels TRPA1, TRPV1, TRPV2, TRPV3, PPAR, 5-HT1A, and A1A, and as an antagonist of the receptors GPR55, GPR18, and 5HT3A (see Table 2 for references)

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Similar to the adult rat TBI model study by Shuhmann et al., we observed significant decrease in concentrations of several neurometabolites in the ipsilateral hippocampus at 24 h post TBI