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H3R antagonists such as ciproxifan have also been effective in enhancing alertness and memory [60], alleviating repetitive behavior in VPA-exposed mice [62], and correcting aberrant histamine-modulated neural activity in the cortico-basal ganglia circuitry [63,64] (Figure 1)

Solvents were from Fisher Scientific

Inclusive recruitment strategies and global research equity are also imperative to ensure that trials reflect the diversity of patient experiences and are generalizable across populations

The functions of the other forms of vitamin E are even less well-understood, although -tocopherol is a nucleophile that may react with electrophilic mutagens, and tocotrienols may be important in protecting neurons from damage