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In comparison to HDACi, PROTAC has diverse advantageous properties notably development of selective HDAC isozyme inhibitor and prevention of drug resistance

This is particularly important in tissues that are highly susceptible to oxidative damage, such as the liver and lungs

One compound that continues to gain attention is AOD-9604

And so, you know, but now that we're proceeding and we're getting, you know, randomized control trials and meta-analyses, meta analytic data, you know, from those trials, like to me it's just, um, we never should have demonized, you know, it's, it's almost as if re nutrition researchers