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Why are the levels low in depression

below 3000 concerning most important clinical, biochemical and disease features: age (p=0.18), sex (p=0.31), BMI (p=0.34), advanced fibrosis stage (p=0.55), LSM values (p=0.73), disease duration (p=0.78), UDCA response (p=0.45), ALT (p=0.97), ALP (p=0.78) values and ALP ULN categories ( 2 ULN, p=0.84), gGT (p=0.49) and IgM (p=0.84) values

Many physiopathological processes, both normal and abnormal, have been associated with DNA methylation (especially 5mC) (see Fig

However, dosing regimens, administration routes, and treatment durations vary considerably across these studies, making direct comparisons challenging (Pickart & Margolina, 2018)