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Both mitochondria and the ER maintain separate pools of GSH, independently regulated apart from the cytosolic GSH pool

Obsessive-compulsive symptoms in psychotic disorderspathogenesis and treatment [German]

In addition, SFN-treated animals also demonstrated reduced levels of mRNA expression of transforming growth factor beta (TGF-) 1, collagen IV, and fibronectin, as well as decreased protein levels when assessed via immunohistochemistry [102]

Future research that identifies supplementary de-nitrosylating proteins may provide valuable information for the removal of SNO-modification and rescuing PD pathology