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These may indicate the infection has spread to the kidneys (pyelonephritis), for which nitrofurantoin is not effective and a different antibiotic is required

Interestingly, while Mlkl / and Mlkl AA mice showed high protection against AAA development, Ripk1 D138N/D138N mice were only partially protected from aortic dilation compared to WT mice, indicating that AAA formation is in part independent of RIPK1-induced apoptosis

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25, 285291 10.1002/jmr.2170 [DOI] [PubMed] [Google Scholar] Giuliani A