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The resistance to anti-AR therapy is acquired by this variant which more efficiently converts the androgen synthesis inhibitor abiraterone into the precursor of potent AR agonist (113)

It has helped to emphasize the importance of introducing new product lines and preserving a steady, high-quality raw material supply through mergers and acquisitions

Cai J, Yue J, Lu N, Li S, Zheng J, Huang R, Jiang Y, Shan C, Liu W, Ma J, Wang L (2024) Association of fat mass and skeletal muscle mass with cardiometabolic risk varied in distinct PCOS subtypes: a propensity score-matched case-control study

At the very least, patients may benefit from being warned that the symptom may be exacerbated by febrile infections and during the perimenstrual period