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Lafont E, Draber P, Rieser E, Reichert M, Kupka S, de Miguel D, et al

The mediator subunit MED16 transduces NRF2-activating signals into antioxidant gene expression

The use of redox-sensitive mbrB or mchlB and visualization of reduced glutathione via bright-field, fluorescence microscopy or CLSM, by contrast, allows insights into the in vivo situation within the nucleus and cytosol