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Drummer CT, Saaoud F, Jhala NC, Cueto R, Sun Y, Xu K, et al

doi:10.1111/j.1742-4658.2011.08358.x

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242 The overexpression of indoleamine 2,3-dioxygenase 1 (IDO1) and TDO2 in GBM leads to the production of L-kynurenine, which interacts with the aryl hydrocarbon receptor (AHR) on TAMs, further inhibiting immune responses