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Many patients begin to notice improvements in energy and body composition within a few weeks of starting therapy

It also crosses the blood-brain barrier, which has some researchers interested in its potential effects on nerve tissue and spinal injuries

Actomyosin contractility can compromise nuclear integrity by squeezing the nucleus dorsoventrally [191, 192], pulling it [193] or promoting the nuclear influx of cytoplasmic constituents, which in turn pressurizes the nucleus, leading to its rupture [155]

However, the longevity community has taken sharp notice of them because obesity and metabolic dysfunction are among the most potent accelerants of biological aging