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Circulation 107:26012606 Higashi Y, Maruhashi T, Noma K, Kihara Y (2014) Oxidative stress and endothelial dysfunction: Clinical evidence and therapeutic implications

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However, in contrast to their definitive hosts, schistosomes completely depend on a single multifunctional enzyme, thioredoxin glutathione reductase (TGR), to maintain reduced forms of both GSH and Trx 24,25,26 since they lack catalase and show very low levels of glutathione peroxidase 27